BDBM50535139 CHEMBL4579759

SMILES COc1ccccc1N1CCN(CCCn2nnnc2C(c2ccccc2)c2ccccc2)CC1

InChI Key InChIKey=HVOHLUNNYMNOQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50535139   

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50535139(CHEMBL4579759)
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]-5-norepinephrine reuptake in human NET expressed in HEK293 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50535139(CHEMBL4579759)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of [3H]-5-dopamine reuptake in human DAT expressed in HEK293 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50535139(CHEMBL4579759)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]-5-hydroxytryptamine reuptake in human SERT expressed in HEK293 cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed