BDBM50535216 CHEMBL4472840

SMILES CC(C)Oc1ccc(Nc2ncc3CN(CCc3n2)C(=O)CCc2ccc3[nH]c(=O)oc3c2)cc1

InChI Key InChIKey=GFOXRASESXUIGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535216   

TargetAutotaxin(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535216(CHEMBL4472840)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50535216(CHEMBL4472840)
Affinity DataIC50: 87nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed