BDBM50535536 CHEMBL4544087

SMILES COc1cc(OC)c(C(=O)Nc2c[nH]nc2C(=O)NC2CCN(CC2)S(=O)(=O)c2cccc(NC(=O)C=C)c2)c(OC)c1

InChI Key InChIKey=VODCPWQTCXGQLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535536   

TargetCyclin-dependent kinase 14(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50535536(CHEMBL4544087)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLAG-tagged CDK14 (unknown origin) expressed in human HEK293 cells assessed as blocking of CDK14 pulldown incubated for 4 hrs by biotin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCyclin-Y(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50535536(CHEMBL4544087)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed