BDBM50535643 CHEMBL4579292

SMILES O[C@@H]1CCN(C[C@@H]1F)c1cc(ncn1)-n1ncc2ccc(cc12)C1(CC2(CC2)C1)C#N

InChI Key InChIKey=WHTWJSNINFWOHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535643   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535643(CHEMBL4579292)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed