BDBM50535650 CHEMBL4540255

SMILES OC(=O)c1ccc(cc1Cl)C(=O)N1CCc2nc([nH]c(=O)c2C1)-c1ccccc1

InChI Key InChIKey=BAWGXTCIJMOEGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535650   

LigandPNGBDBM50535650(CHEMBL4540255)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant MTHFD2 (unknown origin) assessed as reduction in methenyl-THF formation using tetrahydrofolate, NAD and formaldehyde incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed