BDBM50535672 CHEMBL4593073

SMILES CN1c2ccc(cc2CS1(=O)=O)C(=O)N1CCc2nc([nH]c(=O)c2C1)-c1ccccc1

InChI Key InChIKey=SIFOJXGOKNYARJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535672   

TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
Daiichi Sankyo

Curated by ChEMBL

LigandBDBM50535672(CHEMBL4593073)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant MTHFD2 (unknown origin) assessed as reduction in methenyl-THF formation using tetrahydrofolate, NAD and formaldehyde incuba...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/28/2021
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