BDBM50535679 CHEMBL4566424

SMILES O=c1[nH]c2CN(Cc3ccccc3)CCc2c(=O)[nH]1

InChI Key InChIKey=DYNBNPAECUWPPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535679   

TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535679(CHEMBL4566424)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535679(CHEMBL4566424)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed