BDBM50535680 CHEMBL4452842

SMILES OC(=O)CCCCSc1ncnc2[nH]c(=O)[nH]c12

InChI Key InChIKey=AOTNURUEMMPART-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535680   

TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535680(CHEMBL4452842)
Affinity DataIC50: 518nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535680(CHEMBL4452842)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed