BDBM505357 US11066413, Compound 26::US11066413, Compound 42

SMILES Cc1ccc(o1)-c1nc(N)nc2C(Cc3ccc(F)cc3F)OC(=O)c12

InChI Key InChIKey=DKURXUNULYCZBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505357   

TargetAdenosine receptor A2a(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM505357(US11066413, Compound 42 | US11066413, Compound 26)
Affinity DataIC50: 32.1nMAssay Description:1. Preparation of the reagents1) Detection buffer: 50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 1 mM EDTA, 1 μg/mL Adenosine Deaminase, and stored at 4° ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM505357(US11066413, Compound 42 | US11066413, Compound 26)
Affinity DataIC50: 87.4nMAssay Description:1. Preparation of the reagents1) Detection buffer: 50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 1 mM EDTA, 1 μg/mL Adenosine Deaminase, and stored at 4° ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
US Patent