BDBM50535752 CHEMBL4447399

SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2)nc1-c1cc2cnccc2s1

InChI Key InChIKey=MCBWWEZTLDGOCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535752   

TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535752(CHEMBL4447399)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535752(CHEMBL4447399)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant untagged p38alpha expressed in Escherichia coli using ATF2 as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed