BDBM50535762 CHEMBL4563330

SMILES O=C(CNC(=O)c1ccccc1)N1CCC(Cc2nc(no2)C2CC2)CC1

InChI Key InChIKey=KEAGXERJQJPUCK-UHFFFAOYSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50535762   

TargetL-lactate dehydrogenase A chain(Human)
The 5Th Affiliated Hospital of Shenzhen University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50535762(CHEMBL4563330)
Affinity DataEC50:  700nMAssay Description:Inhibition of His-tagged human LDHA incubated for 10 mins using NADH and pyruvate by microplate reader based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
The 5Th Affiliated Hospital of Shenzhen University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50535762(CHEMBL4563330)
Affinity DataKd:  1.02E+3nMAssay Description:Binding affinity to His-tagged human LDHA in presence of NAD+ by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
The 5Th Affiliated Hospital of Shenzhen University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50535762(CHEMBL4563330)
Affinity DataKd:  4.32E+4nMAssay Description:Binding affinity to His-tagged human LDHA in absence of NAD+ by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed