BDBM50535943 CHEMBL4548499

SMILES FC(F)(F)Oc1ccc(CN2CCC(CC2)C(=O)Nc2nc(c(s2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=GLSFHIYDEXRABI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535943   

TargetAcetylcholinesterase(Human)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535943(CHEMBL4548499)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human erythrocyte AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535943(CHEMBL4548499)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed