BDBM50536026 CHEMBL4549558

SMILES O=C(N1CCc2c([nH]c3ccccc23)C1c1cccc(c1)C#N)c1ccccc1

InChI Key InChIKey=JFYIGAAQIDTDQO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536026   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50536026(CHEMBL4549558)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux pre-incubated for 30 mins before Hoechst 33342 addit...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/28/2021
Entry Details Article
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TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50536026(CHEMBL4549558)Copy SMILESCopy InChI

Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of ABCB1 in human A2780/ADR cells assessed as reduction in calcein AM efflux pre-incubated for 30 mins before calcein AM addition and meas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/28/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL