BDBM50536619 CHEMBL4516136

SMILES Nc1c(sc2nc(O)c3CCCCc3c12)C(=O)c1ccncc1

InChI Key InChIKey=PODWKHQMHGCPBB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536619   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50536619(CHEMBL4516136)
Affinity DataEC50:  75.9nMAssay Description:Positive allosteric modulation activity at human M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50536619(CHEMBL4516136)
Affinity DataEC50:  76nMAssay Description:Positive allosteric modulation activity at human M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50536619(CHEMBL4516136)
Affinity DataEC50:  182nMAssay Description:Positive allosteric modulation activity at rat M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50536619(CHEMBL4516136)
Affinity DataEC50:  182nMAssay Description:Positive allosteric modulation activity at rat M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed