BDBM50536816 CHEMBL4577046

SMILES COc1ncc(cc1C#N)-c1ccc2ncnc(NCCN3CCOCC3)c2c1

InChI Key InChIKey=GNJXDCIDKCOMEA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536816   

LigandPNGBDBM50536816(CHEMBL4577046)
Affinity DataIC50: 934nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
LigandPNGBDBM50536816(CHEMBL4577046)
Affinity DataIC50: 37nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
LigandPNGBDBM50536816(CHEMBL4577046)
Affinity DataIC50: 465nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
LigandPNGBDBM50536816(CHEMBL4577046)
Affinity DataIC50: 300nMAssay Description:Inhibition of PI3Kbeta (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed