BDBM50536818 CHEMBL4539481

SMILES COc1ncc(cc1C#N)-c1ccc2ncnc(NCCN(C)C)c2c1

InChI Key InChIKey=ONSUZQUHZXIMBX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536818   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Xi'An Jiaotong University

Curated by ChEMBL

LigandBDBM50536818(CHEMBL4539481)Copy SMILESCopy InChI

Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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