BDBM50536824 CHEMBL4552375

SMILES Cc1cc2ccc(Nc3cccnn3)cc2n1-c1cccnc1Cl

InChI Key InChIKey=BMVRTXLBNWGHKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536824   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50536824(CHEMBL4552375)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of DOT1L (2 to 416 residues) (unknown origin) using biotinylated nucleosomes as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed