BDBM50536850 CHEMBL4570064

SMILES FCC(=O)CNC(=O)[C@H](Cc1cccc(F)c1)NC(=O)OCc1ccccc1

InChI Key InChIKey=MSTHTKTWGVWYNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536850   

TargetCysteine protease ATG4B(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50536850(CHEMBL4570064)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50536850(CHEMBL4570064)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed