BDBM50537349 CHEMBL4574380

SMILES Nc1n[nH]c2ccc(NC(=O)c3ccccc3Cl)cc12

InChI Key InChIKey=XVIOSMUOJJRPNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537349   

TargetTyrosine-protein kinase JAK2(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50537349(CHEMBL4574380)
Affinity DataIC50: 101nMAssay Description:Inhibition of JAK2 (unknown origin) after 1 hr FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50537349(CHEMBL4574380)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of JAK1 (unknown origin) after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed