BDBM50537746 CHEMBL4645353

SMILES Fc1ccc(cc1)-n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(=O)c2ccccc12

InChI Key InChIKey=DNSSISOAGFXBRM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50537746   

TargetHepatocyte growth factor receptor(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 17nMAssay Description:Inhibition of c-Met (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of c-Kit (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of FLT3 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RON (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537746(CHEMBL4645353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed