BDBM50537765 CHEMBL4642944

SMILES O=C(CCC(=O)N1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4[nH]ccc34)cc2)CC1)NCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

InChI Key InChIKey=BRYMZSSAIDEFEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537765   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50537765(CHEMBL4642944)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of tracer K10 binding to NanoLuc-CDK2/Cyclin A (unknown origin) expressed in human HEK293 cells after 1 hr in presence of ATP by NanoBRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50537765(CHEMBL4642944)
Affinity DataIC50: 15nMAssay Description:Inhibition of tracer K10 binding to NanoLuc-CDK9/Cyclin T1 (unknown origin) expressed in human HEK293 cells after 1 hr in presence of ATP by NanoBRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed