BDBM50537886 CHEMBL4647499

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COC(=O)c2cc[nH]c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=JXFASNVVYCKOKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50537886   

TargetRibosomal protein S6 kinase alpha-3(Human)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50537886(CHEMBL4647499)
Affinity DataIC50: 970nMAssay Description:Inhibition of His-tagged recombinant human RSK2 expressed in baculovirus expression system after 1 hr by by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50537886(CHEMBL4647499)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-Terminal GST tagged human GSK3A expressed in baculovirus expression system after 1 hr by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50537886(CHEMBL4647499)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of human MAPK14 expressed in Escherichia coli after 1 hr by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed