BDBM50538116 CHEMBL4641351

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3C)n2)nc1

InChI Key InChIKey=SKKBWFDITHTKEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538116   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538116(CHEMBL4641351)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged CDK6/cyclinD3 expressed in baculovirus infected Sf9 insect cells using histone H1 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCyclin-K(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538116(CHEMBL4641351)
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CDK9/cyclinK expressed in baculovirus infected Sf9 insect cells using PDKtide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538116(CHEMBL4641351)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CDK2/cyclinA2 expressed in baculovirus infected Sf9 insect cells using histone H1 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed