BDBM50538143 CHEMBL4643225

SMILES CC(C)c1ccc(Nc2nc(Nc3ccc(cn3)N3CCN(C)CC3)ncc2Cl)cc1

InChI Key InChIKey=VCHBBLKMWHUOMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538143   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538143(CHEMBL4643225)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged CDK6/cyclinD3 expressed in baculovirus infected Sf9 insect cells using histone H1 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCyclin-K(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538143(CHEMBL4643225)
Affinity DataIC50: 9.17E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CDK9/cyclinK expressed in baculovirus infected Sf9 insect cells using PDKtide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50538143(CHEMBL4643225)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged CDK2/cyclinA2 expressed in baculovirus infected Sf9 insect cells using histone H1 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed