BDBM50538338 CHEMBL4643370

SMILES Cc1[nH]c(C(=O)NC2CC2)c(C)c1Cc1ccc(nc1)C(F)(F)F

InChI Key InChIKey=MPFACFTUZVDOPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538338   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Birla Institute of Technology and Science Pilani

Curated by ChEMBL
LigandPNGBDBM50538338(CHEMBL4643370)
Affinity DataIC50: 50nMAssay Description:Inhibition of Plasmodium falciparum DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538338(CHEMBL4643370)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538338(CHEMBL4643370)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed