BDBM50538365 CHEMBL4632920

SMILES CCCNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=PTZCOTMMBQEIKX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538365   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538365(CHEMBL4632920)Copy SMILESCopy InChI

Affinity DataIC50: 447nMAssay Description:Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetSolute carrier family 2, facilitated glucose transporter member 3(Human)
Kadmon

Curated by ChEMBL

LigandBDBM50538365(CHEMBL4632920)Copy SMILESCopy InChI

Affinity DataIC50: 298nMAssay Description:Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL