BDBM50538518 CHEMBL4639162

SMILES [H][C@]12CNC[C@@]1([H])[C@H](CCCB(O)O)[C@@](N)(C2)C(O)=O

InChI Key InChIKey=XIEAQQGNISCWOO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50538518   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50: 29nMAssay Description:Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50: 148nMAssay Description:Inhibition of arginase1 in human cancer patient serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50: 361nMAssay Description:Inhibition of arginase1 in human HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetArginase-1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50538518(CHEMBL4639162)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of arginase1 in mouse BMDM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed