BDBM50538923 CHEMBL4646768

SMILES CCN1C(=O)c2ccc(cc2C1(C)C)-c1c(C)nc2c(OCc3ccccc3)cccn12

InChI Key InChIKey=SHEROKXHUJHVBP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538923   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50538923(CHEMBL4646768)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2021
Entry Details Article
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