BDBM50538994 CHEMBL4634770

SMILES COc1cc(N2CC(C2)Nc2ncnc3c4c(C)n(C)nc4ccc23)c(Cl)cn1

InChI Key InChIKey=JMBUQDNWENYELJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538994   

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50538994(CHEMBL4634770)
Affinity DataEC50:  226nMAssay Description:Positive allosteric modulation of rat muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50538994(CHEMBL4634770)
Affinity DataEC50:  379nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed