BDBM50539571 CHEMBL4635896

SMILES Cn1nnc2cc(ccc12)C(CC(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1ccccc1

InChI Key InChIKey=HQMUAYQNXJIIGH-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539571   

TargetKelch-like ECH-associated protein 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50539571(CHEMBL4635896)
Affinity DataKd:  56nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50539571(CHEMBL4635896)
Affinity DataEC50:  9.50E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed