BDBM50539806 CHEMBL4633481

SMILES Cc1[nH]nc2[nH]c(=O)cc(C(F)F)c12

InChI Key InChIKey=SGQLQUJVSPTQNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539806   

TargetTyrosine-protein kinase JAK1(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50539806(CHEMBL4633481)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50539806(CHEMBL4633481)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 (850 to 1154 residues) expressed in baculovirus expression system using TK-substrate-biotin as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed