BDBM50540613 CHEMBL4641588

SMILES Cc1cc(=O)oc2cc(NC(=O)CCN3C(=O)C4=C(SC[C@@H](NC(=O)[C@@H](N)Cc5ccc(O)cc5)C(=O)NCC(=O)N[C@@H](Cc5ccccc5)C(=O)NNC(=O)[C@H](Cc5ccccc5)NC(=O)CNC(=O)[C@@H](CS4)NC(=O)[C@@H](N)Cc4ccc(O)cc4)C3=O)ccc12

InChI Key InChIKey=TZISJHJRDIAPKU-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50540613   

TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi:  510nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed