BDBM50540615 CHEMBL4638703

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCN1C(=O)C2=C(SC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)NNC(=O)[C@H](Cc3ccccc3)NC(=O)CNC(=O)[C@@H](CS2)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O

InChI Key InChIKey=KBCSNKLJZVBEDT-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50540615   

TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed