BDBM50540764 CHEMBL4648322

SMILES COc1cc2c(cc1OC)OC(=O)C(=C2)NC(=O)[C@@H]3CCC[C@@H](C3)NCc4ccccc4

InChI Key InChIKey=UGTGSTDFYWUXNH-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540764   

TargetAcetylcholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50540764(CHEMBL4648322)
Affinity DataKi:  19nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50540764(CHEMBL4648322)
Affinity DataIC50: 19nMAssay Description:Inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50540764(CHEMBL4648322)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed