BDBM50541328 CHEMBL4646299

SMILES [#6]-[#8]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@H]-1-c1ccccc1

InChI Key InChIKey=BKJMBQMPEQUSLA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541328   

TargetApoptosis regulator Bcl-2(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541328(CHEMBL4646299)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541328(CHEMBL4646299)
Affinity DataKi: >2.30E+4nMAssay Description:Inhibition of Bcl-xL (unknown origin)/Bak interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541328(CHEMBL4646299)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of Mcl-1 (unknown origin)/Bid interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed