BDBM50541332 CHEMBL4635324

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6@H](-[#6@@H](-[#6]-1)-c1ccccc1)-[#6](=O)-[#7]-[#8]

InChI Key InChIKey=JBORLGVMTGECAC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541332   

TargetApoptosis regulator Bcl-2(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541332(CHEMBL4635324)
Affinity DataKi:  700nMAssay Description:Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541332(CHEMBL4635324)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of Mcl-1 (unknown origin)/Bid interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50541332(CHEMBL4635324)
Affinity DataKi:  1.74E+4nMAssay Description:Inhibition of Bcl-xL (unknown origin)/Bak interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed