BDBM50541989 CHEMBL4638559

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1ccnc(OC)c1)[C@H]2Nc1nc2N(CCCn2n1)c1ccc(F)c(F)c1

InChI Key InChIKey=PDOHVGKIOMMAAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541989   

TargetPresenilin-1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50541989(CHEMBL4638559)
Affinity DataIC50: 16nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50541989(CHEMBL4638559)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed