BDBM50542064 CHEMBL4634750

SMILES NC(=O)C([C@@H]1CCN(CCOc2ccc(cc2)-c2nnco2)C1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DZRWSMKTZQSXKI-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542064   

TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataKi:  4.09E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542064(CHEMBL4634750)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed