BDBM50542076 CHEMBL4643803

SMILES C[C@@]1(CC[C@H](CC(=O)N2CCc3c(C2)n(Cc2ccc(F)cc2F)c2ncccc32)CC1)C(O)=O

InChI Key InChIKey=ITUYIHBIYFMSGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542076   

TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542076(CHEMBL4643803)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542076(CHEMBL4643803)
Affinity DataIC50: 25nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed