BDBM50543679 CHEMBL4648849
SMILES CCN(CC)C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)S(=O)(=O)N[C@@H](C)C(F)(F)F)-c1nnc(o1)C(C)(C)O
InChI Key InChIKey=TZBMJMWWRPOUKP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50543679
Affinity DataKd: 5nMAssay Description:Binding affinity to RORgammat (unknown origin) assessed as dissociation constant by thermal shift binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Binding affinity to recombinant human RORgammat transfected in human HEK293T cells incubated for 24 hrs by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inverse agonist activity at RORgammat in human whole blood assessed as reduction in IL-17a productionMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inverse agonist activity at RORgammat in mouse whole blood assessed as reduction in IL-17a productionMore data for this Ligand-Target Pair
Affinity DataKd: >6.00E+4nMAssay Description:Binding affinity to RORbeta (unknown origin) assessed as dissociation constant by thermal shift binding assayMore data for this Ligand-Target Pair
