BDBM50543924 CHEMBL4642137

SMILES O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)NCC#N)n2n1)C1CC1

InChI Key InChIKey=VGSIYWUGYCKFJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543924   

TargetTyrosine-protein kinase JAK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543924(CHEMBL4642137)
Affinity DataIC50: 286nMAssay Description:Inhibition of JAK1 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543924(CHEMBL4642137)
Affinity DataIC50: 299nMAssay Description:Inhibition of JAK2 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543924(CHEMBL4642137)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of JAK3 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed