BDBM50543929 CHEMBL4636957

SMILES O=C(Nc1nc2cccc(C3=CCN(CC3)C(=O)NCC#N)n2n1)C1CC1

InChI Key InChIKey=RXRJJVKGIFEVSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543929   

TargetTyrosine-protein kinase JAK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543929(CHEMBL4636957)
Affinity DataIC50: 170nMAssay Description:Inhibition of JAK1 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543929(CHEMBL4636957)
Affinity DataIC50: 175nMAssay Description:Inhibition of JAK2 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543929(CHEMBL4636957)
Affinity DataIC50: 983nMAssay Description:Inhibition of JAK3 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed