BDBM50544506 CHEMBL4647464

SMILES COC(=O)CC[C@H]1N[C@@H](Cc2c1[nH]c1ccccc21)C(=O)NCc1ccc(F)cc1

InChI Key InChIKey=BWDFPQXMRYCTCK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544506   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
University of Salerno

Curated by ChEMBL

LigandBDBM50544506(CHEMBL4647464)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
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TargetTransient receptor potential cation channel subfamily M member 8(Human)
University of Salerno

Curated by ChEMBL

LigandBDBM50544506(CHEMBL4647464)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK-293/TRPM8 exon1 K3 cells assessed as inhibition of menthol-induced current response by whole-cell...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL