BDBM50544513 CHEMBL4649088

SMILES O=C1N[C@H](Cc2ccccc2)C(=O)N2Cc3[nH]c4ccccc4c3C[C@@H]12

InChI Key InChIKey=RADKAGRBIKGFHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544513   

LigandChemical structure of BindingDB Monomer ID 50544513BDBM50544513(CHEMBL4649088)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK-293/TRPM8 exon1 K3 cells assessed as inhibition of menthol-induced current response by whole-cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50544513BDBM50544513(CHEMBL4649088)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed