BDBM50544531 CHEMBL4648953

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@@H](N1C(=O)N(C2=O)c1cccc(c1)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=BKIVSJZNZNFDNY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544531   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
University of Salerno

Curated by ChEMBL

LigandBDBM50544531(CHEMBL4648953)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
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TargetTransient receptor potential cation channel subfamily M member 8(Human)
University of Salerno

Curated by ChEMBL

LigandBDBM50544531(CHEMBL4648953)Copy SMILESCopy InChI

Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK-293/TRPM8 exon1 K3 cells assessed as inhibition of menthol-induced current response by whole-cell...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL