BDBM50544741 CHEMBL4644715

SMILES COCCNC(=O)[C@H](CCc1ccccc1)NC(=O)c1cc(-c2c(OC)cccc2OC)n(CC(C)C)n1

InChI Key InChIKey=LRDNILHXWHZULD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544741   

TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544741(CHEMBL4644715)
Affinity DataEC50:  411nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells co-expressing Galphaq16 assessed as increase in intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544741(CHEMBL4644715)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50544741(CHEMBL4644715)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHOK1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed