BDBM50544755 CHEMBL4645357

SMILES CCN(C1CCOCC1)c1cc(\C=C\c2cccc(CN(C)C)c2)cc(C(=O)NCc2c3CCCCc3c(C)[nH]c2=O)c1C

InChI Key InChIKey=XARNHVZJVUZYMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544755   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544755(CHEMBL4645357)
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544755(CHEMBL4645357)
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type EZH2 (unknown origin) in presence of 1 uM SAM by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed