BDBM50545181 CHEMBL4633117

SMILES CC1(C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

InChI Key InChIKey=BSLQJJPIELRITP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50545181   

TargetIntegrin alpha-V/beta-3(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 50nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 141nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 378nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 806nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed