BDBM50545463 CHEMBL4643652

SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OCC(O)=O)c2)n1

InChI Key InChIKey=HDDJGLQYFZACAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545463   

TargetFibroblast growth factor receptor 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50545463(CHEMBL4643652)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50545463(CHEMBL4643652)
Affinity DataIC50: 120nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR2 cytoplasmic domain (790-1356 end amino acid residue) expressed in baculovirus expression system prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed