BDBM50545470 CHEMBL4646707

SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1Cc1cc(OC)cc(OC)c1

InChI Key InChIKey=MHHSLKCQZMRDAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545470   

TargetFibroblast growth factor receptor 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50545470(CHEMBL4646707)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50545470(CHEMBL4646707)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR2 cytoplasmic domain (790-1356 end amino acid residue) expressed in baculovirus expression system prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed